YjbH - Revision history

Jstuelk at 14:40, 15 June 2015

2015-06-15T14:40:09Z

Jstuelk at 16:36, 3 February 2015

2015-02-03T16:36:03Z

Jstuelk at 12:28, 31 October 2014

2014-10-31T12:28:04Z

Jstuelk: /* Original Publications */

2014-06-20T10:51:05Z

‎Original Publications

134.76.38.147 at 13:25, 2 April 2014

2014-04-02T13:25:24Z

Jstuelk at 09:33, 16 January 2014

2014-01-16T09:33:25Z

134.76.70.252 at 16:00, 11 November 2013

2013-11-11T16:00:44Z

134.76.70.252 at 12:59, 16 May 2013

2013-05-16T12:59:19Z

134.76.70.252 at 09:55, 14 May 2013

2013-05-14T09:55:13Z

134.76.70.252 at 12:33, 13 May 2013

2013-05-13T12:33:08Z

← Older revision		Revision as of 14:40, 15 June 2015
Line 1:		Line 1:
−	* '''Description:''' adaptor protein for [[ClpX]]-[[ClpP]]-catalyzed [[Spx]] degradation, confers resistance against nitrosating agents <br/><br/>	+	{{#bank: YjbH}}
−	{~~\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''yjbH''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| adaptor protein~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| stimulation of [[Spx]] degradation~~
−	\|-
−	~~\|colspan="2" style="background:~~#~~FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http~~:~~//subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU11550 yjbH]~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YjbH ~~YjbH]~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 31 kDa, 5.206~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 825 bp, 275 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[roxS]]'', ''[[yjbI]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU11550 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU11550 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU11550 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:yjbH_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	~~\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yjbH_1233614_1234513_-1 Expression at a glance]'''   {{PubMed\|22383849~~}~~}<br/>[[Image:yjbH_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU11550]]~~
−	\|-
−	\|}

−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[proteolysis]]}},~~
−	~~{{SubtiWiki category\|[[resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU11550
−
−	~~===Phenotypes of a mutant ===~~
−	* increased thermotolerance due to increased stabiliy of [[Spx]] and thus increased expression of ''[[trxA]]'' {{PubMed\|24417481}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11550&redirect=T BSU11550]
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13137]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:''' adaptor protein for [[ClpX]]-[[ClpP]]-catalyzed [[Spx]] degradation [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed]
−
−	* '''Protein family:''' UPF0413 family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−	** contains Zn atoms (coordinated by the N-terminal His-rich region) [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed]
−
−	* '''Effectors of protein activity:'''
−	** [[YjbH]] aggregates under stress conditions, resulting in the inability to bind to [[Spx]], and therefore in stabilization of [[Spx]] {{PubMed\|25353645}}
−	** Zn atom is released upon treatment with strong oxidants [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed]
−	** interaction with [[YirB]] inhibits the formation of a complex with [[Spx]] {{PubMed\|21378193}}
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[YjbH]]-[[Spx]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed]
−	** [[YirB]]-[[YjbH]] {{PubMed\|21378193}}
−
−	* '''[[Localization]]:''' cytosolic protein
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11550&redirect=T BSU11550]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/O31606 O31606]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU11550]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[yjbI]]-[[yjbH]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/17293416 PubMed]
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yjbH_1233614_1234513_-1 yjbH] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−
−	* '''Regulation:'''
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−	** A [[ncRNA]] is predicted between ''[[yizD]]'' and ''[[yjbH]]'' {{PubMed\|20525796}}
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~[[Peter Zuber]], Oregon Health and Science University, USA~~
−	~~[http://www.ogi.edu/people/dsp_person.cfm?person_id=411D6801-2A56-D16D-58A06B4480EDB9C7 Homepage]~~
−
−	~~[[Claes von Wachenfeldt]], Lund University, Sweden [http://aron.ldc.lu.se/kundwebb/cellorg/mibiol/research/wachen/index.htm Homepage]~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed> 23375660 23479438,19609260</pubmed>~~
−	~~==Original Publications==~~
−	~~<pubmed>17293416, 19074380 17908206, 20525796 21378193,21947404 24417481 24942655 25353645 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 21: / Line 21: @@
 |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 825 bp, 275 aa
 |-
-|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yizD]]'', ''[[yjbI]]''
+|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[roxS]]'', ''[[yjbI]]''
 |-
 |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU11550 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU11550 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU11550 DNA_with_flanks]

@@ Line 85: / Line 85: @@
 * '''Effectors of protein activity:'''
 ** Zn atom is released upon treatment with strong oxidants [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed]
 ** interaction with [[YirB]] inhibits the formation of a complex with [[Spx]] {{PubMed|21378193}}
@@ Line 149: / Line 150: @@
 <pubmed> 23375660 23479438,19609260</pubmed>
 ==Original Publications==
-<pubmed>17293416, 19074380 17908206, 20525796 21378193,21947404 24417481 24942655 </pubmed>
+<pubmed>17293416, 19074380 17908206, 20525796 21378193,21947404 24417481 24942655 25353645 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 149: / Line 149: @@
 <pubmed> 23375660 23479438,19609260</pubmed>
 ==Original Publications==
-<pubmed>17293416, 19074380 17908206, 20525796 21378193,21947404 24417481</pubmed>
+<pubmed>17293416, 19074380 17908206, 20525796 21378193,21947404 24417481 24942655 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 55: / Line 55: @@
 === Database entries ===
 * '''DBTBS entry:''' no entry
@@ Line 94: / Line 95: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 52: / Line 52: @@
 ===Phenotypes of a mutant ===
 === Database entries ===
@@ Line 75: / Line 76: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''contains Zn atoms (coordinated by the N-terminal His-rich region) [http://www.ncbi.nlm.nih.gov/sites/entrez/19074380 PubMed]
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 143: / Line 145: @@
 =References=
 ==Reviews==
-'''Additional reviews:''' {{PubMed|23479438,19609260}}
+<pubmed> 23375660 23479438,19609260</pubmed>
 ==Original Publications==
-'''Additional publications:''' {{PubMed|21378193,21947404}}
+<pubmed>17293416, 19074380 17908206, 20525796 21378193,21947404 24417481</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 15: / Line 15: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU11550 yjbH]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/YjbH YjbH]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=YjbH YjbH]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 5.206

@@ Line 28: / Line 28: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yjbH_1233614_1234513_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yjbH_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yjbH_1233614_1234513_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yjbH_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU11550]]
 |-
 |}

@@ Line 23: / Line 23: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yizD]]'', ''[[yjbI]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU11550 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU11550 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU11550 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU11550 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU11550 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU11550 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:yjbH_context.gif]]