ThiT - Revision history

134.76.38.147 at 14:36, 2 April 2014

2014-04-02T14:36:13Z

Jstuelk at 11:56, 10 January 2014

2014-01-10T11:56:48Z

134.76.70.252 at 11:32, 7 January 2014

2014-01-07T11:32:19Z

Jstuelk: /* References */

2013-12-27T17:48:25Z

‎References

Jstuelk: /* Reviews */

2013-12-27T17:25:01Z

‎Reviews

134.76.70.252 at 14:19, 18 November 2013

2013-11-18T14:19:59Z

Jstuelk at 19:28, 13 July 2013

2013-07-13T19:28:25Z

Jstuelk: /* References */

2013-07-13T19:25:55Z

‎References

Jstuelk: /* Extended information on the protein */

2013-07-13T19:23:16Z

‎Extended information on the protein

Jstuelk at 15:11, 13 July 2013

2013-07-13T15:11:41Z

← Older revision		Revision as of 14:36, 2 April 2014
Line 1:		Line 1:
−	* '''Description:~~''' S protein of thiamine [[ECF transporter]]<br/><br/>~~	+	{{#bank: ThiT}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''thiT''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''yuaJ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| S protein of thiamine [[ECF transporter]]~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| thiamine uptake~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30990 thiT]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ThiT ThiT]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=thiT thiT]'''
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 20 kDa, 10.237~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 576 bp, 192 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[rrnB-16S]]'', ''[[yuaI]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30990 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30990 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30990 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:yuaJ_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thiT_3179306_3179884_1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:thiT_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30990]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[ECF transporter]]}},~~
−	~~{{SubtiWiki category\|[[biosynthesis of cofactors]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[Thi-box]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU30990
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−
−	* '''DBTBS entry:''' no entry
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13949]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:''' proton-coupled thiamine transporter family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[YbaF]]-[[ThiT]] {{PubMed\|20497229}}
−
−	* '''[[Localization]]:'''
−	** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
−
−	~~=== Database entries ===~~
−
−	* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=3RLB 3RLB] (from ''Lactococcus lactis'', 32% identity) {{PubMed\|21706007}}
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/O32074 O32074]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU30990]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:'''
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=thiT_3179306_3179884_1 thiT] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−
−	* '''Regulation:'''
−	** repressed by thiamine ([[Thi-box]]) {{PubMed\|12376536}}
−
−	* '''Regulatory mechanism:'''
−	** [[Thi-box]]: [[RNA switch]] {{PubMed\|12376536}}
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed> 20497229 22574898 24362466 </pubmed>~~
−	~~==Original publications==~~
−	~~<pubmed>16291685, 21706007,18763711, 12376536 23602660</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 64: / Line 64: @@
 === Additional information===
 =The protein=
@@ Line 82: / Line 79: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 144: / Line 141: @@
 =References=
 ==Reviews==
-<pubmed> 20497229 22574898</pubmed>
+<pubmed> 20497229 22574898 24362466 </pubmed>
 ==Original publications==
 <pubmed>16291685, 21706007,18763711, 12376536 23602660</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 18: / Line 18: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ThiT ThiT]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=thiT thiT]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 20 kDa, 10.237

@@ Line 145: / Line 145: @@
 ==Reviews==
 <pubmed> 20497229 22574898</pubmed>
 ==Original publications==
-<pubmed>16291685, 21706007,18763711, 12376536</pubmed>
+<pubmed>16291685, 21706007,18763711, 12376536 23602660</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 144: / Line 144: @@
 =References=
 ==Reviews==
-<pubmed> 20497229 </pubmed>
+<pubmed> 20497229 22574898</pubmed>
 ==Original publications==
 <pubmed>16291685, 21706007,18763711, 12376536</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30990 thiT]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ThiT ThiT]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=ThiT ThiT]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/thiamin.html Thiamin]'''

@@ Line 89: / Line 89: @@
 * '''[[SubtInteract|Interactions]]:'''
 * '''[[Localization]]:'''
-** membrane associated [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
+** membrane [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
 === Database entries ===

@@ Line 1: / Line 1: @@
-* '''Description:''' thiamine permease <br/><br/>
+* '''Description:''' S protein of thiamine [[ECF transporter]]<br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 10: / Line 10: @@
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || thiamine permease
+|style="background:#ABCDEF;" align="center"| '''Product''' || S protein of thiamine [[ECF transporter]]
 |-
 |style="background:#ABCDEF;" align="center"|'''Function''' || thiamine uptake
@@ Line 40: / Line 40: @@
 = [[Categories]] containing this gene/protein =
-{{SubtiWiki category|[[transporters/ other]]}},
+{{SubtiWiki category|[[ECF transporter]]}},
 {{SubtiWiki category|[[biosynthesis of cofactors]]}},
 {{SubtiWiki category|[[membrane proteins]]}}