SpoIVCB - Revision history

Jstuelk at 08:34, 10 October 2014

2014-10-10T08:34:46Z

134.76.38.147 at 14:17, 2 April 2014

2014-04-02T14:17:14Z

134.76.70.252 at 08:55, 12 November 2013

2013-11-12T08:55:17Z

Jstuelk at 17:38, 3 September 2013

2013-09-03T17:38:31Z

134.76.70.252 at 13:59, 16 May 2013

2013-05-16T13:59:31Z

134.76.70.252 at 13:22, 13 May 2013

2013-05-13T13:22:10Z

Jstuelk at 13:01, 19 April 2013

2013-04-19T13:01:18Z

134.76.70.252 at 14:02, 7 August 2012

2012-08-07T14:02:52Z

134.76.70.252 at 09:14, 20 April 2012

2012-04-20T09:14:17Z

134.76.70.252 at 11:47, 16 April 2012

2012-04-16T11:47:35Z

← Older revision		Revision as of 08:34, 10 October 2014
Line 1:		Line 1:
−	* '''Description:''' sporulation-specific [[sigma factor]] ([[SigK]]) (N-terminal half), other part: ''[[spoIIIC]]''	+	{{#bank: SpoIVCB}}
−	~~<br/><br/>~~
−	{~~\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:~~#~~ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''spoIVCB''~~
−	\|-
−	~~\|style="background~~:~~#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''cisB, sigK ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| [[RNA polymerase]] sporulation-specific [[sigma factor]] <br/>(sigma-K) (N-terminal half)~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| late mother cell-specific gene expression~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25760 spoIVCB]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SigK SigK]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 17 kDa, 8.208~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 468 bp, 156 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[nucB]]'', ''[[spoIVCA]]''~~
−	\|-
−	~~\|style="background:#FAF8CC;" align="center"\|'''[http://subtiwiki.uni-goettingen.de/spoIVCB_nucleotide.txt Gene sequence (+200bp) ]'''~~
−	~~\|style="background:#FAF8CC;" align="center"\|'''[http://subtiwiki.uni-goettingen.de/spoIVCB_protein.txt Protein sequence]'''~~
−	\|-
−	~~\|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" \| '''Caution: The sequence for this gene in SubtiList contains errors~~
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:spoIVCB_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	~~\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVCB_2652993_2653463_1 Expression at a glance]'''   {{PubMed\|22383849}~~}~~<br/>[[Image:spoIVCB_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25760]]~~
−	\|-
−	\|}

−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[transcription]]}},~~
−	~~{{SubtiWiki category\|[[sigma factors and their control]]}},~~
−	~~{{SubtiWiki category\|[[sporulation proteins]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[GerE regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[SigE regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[SigK regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[SpoIIID regulon]]}}~~
−
−	~~=The [[SigK regulon]]=~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU25760
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25760&redirect=T BSU25760]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIVCB-spoIIIC.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10459]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:''' sigma-70 factor family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[SpoIVFB]]-pro[[SigK]] {{PubMed\|23995631,23585539,19805276}}
−	** [[SigK]]-([[RpoB]]-[[RpoC]])
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25760&redirect=T BSU25760]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P12254 P12254]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU25760]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[sigK]]'' (composed of ''[[spoIVCB]]-[[spoIIIC]]'') {{PubMed\|2536191}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVCB_2652993_2653463_1 spoIVCB] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigE]] {{PubMed\|15699190,2841290}}, [[SigK]] {{PubMed\|2841290}}
−
−	* '''Regulation:'''
−	** expressed during sporulation in the mother cell ([[SigE]], [[SigK]], [[GerE]], [[SpoIIID]]) {{PubMed\|15699190,2841290,10075739,7966271}}
−
−	* '''Regulatory mechanism:'''
−	** [[GerE]]: transcription repression {{PubMed\|10075739}}
−	** [[SpoIIID]]: transcription activation {{PubMed\|7966271}}
−
−	* '''Additional information:'''
−	** [[SigK]] is activated by processing of membrane-bound pro-[[SigK]] by the [[SpoIVFB]] metalloprotease {{PubMed\|23585539,19805276}}
−	** ''spoIVCB'' and ''[[spoIIIC]]'' form a composite gene in the mother cell during sporulation by excising the intervening DNA sequence.
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	* [[Arthur Aronson]], Purdue University, West Lafayette, USA [http://wwwdev.gradschool.purdue.edu/PULSe/faculty.cfm?fid=5&range=0 homepage]
−	* [[Charles Moran]], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed>20833318 20836086 </pubmed>~~
−	~~==The [[SigK regulon]]==~~
−	~~<pubmed>16385044,15383836, 21670523 </pubmed>~~
−
−	~~==Original Publications==~~
−	<pubmed>14526016,17720779,1900494,10438769,2492118,1691789,2536191,2163341,10931284,1577688,9852018,1942049,7814326,8550479,11959848,9501233,10400595,2115401,7592342,1518043,8226681,9078383,2514119,10611287,14523132, 19805276 10075739 7966271 17890309 23585539 23995631 </pubmed>
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 65: / Line 65: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIVCB-spoIIIC.html]
@@ Line 101: / Line 102: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25760 spoIVCB]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SigK SigK]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SigK SigK]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 8.208

@@ Line 95: / Line 95: @@
 * '''[[SubtInteract|Interactions]]:'''
-** [[SpoIVFB]]-pro[[SigK]] {{PubMed|23585539,19805276}}
+** [[SpoIVFB]]-pro[[SigK]] {{PubMed|23995631,23585539,19805276}}
 ** [[SigK]]-([[RpoB]]-[[RpoC]])
@@ Line 159: / Line 159: @@
 ==Original Publications==
-<pubmed>14526016,17720779,1900494,10438769,2492118,1691789,2536191,2163341,10931284,1577688,9852018,1942049,7814326,8550479,11959848,9501233,10400595,2115401,7592342,1518043,8226681,9078383,2514119,10611287,14523132, 19805276 10075739 7966271 17890309 23585539</pubmed>
+<pubmed>14526016,17720779,1900494,10438769,2492118,1691789,2536191,2163341,10931284,1577688,9852018,1942049,7814326,8550479,11959848,9501233,10400595,2115401,7592342,1518043,8226681,9078383,2514119,10611287,14523132, 19805276 10075739 7966271 17890309 23585539 23995631 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 32: / Line 32: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVCB_2652993_2653463_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:spoIVCB_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVCB_2652993_2653463_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:spoIVCB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25760]]
 |-
 |}

@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || late mother cell-specific gene expression
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU25760 spoIVCB]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25760 spoIVCB]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SigK SigK]

@@ Line 40: / Line 40: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
@@ Line 99: / Line 95: @@
 * '''[[SubtInteract|Interactions]]:'''
-** [[SpoIVFB]]-pro[[SigK]] {{PubMed|19805276}}
+** [[SpoIVFB]]-pro[[SigK]] {{PubMed|23585539,19805276}}
 ** [[SigK]]-([[RpoB]]-[[RpoC]])
@@ Line 122: / Line 118: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIVCB_2652993_2653463_1 spoIVCB] {{PubMed|22383849}}
-* '''Sigma factor:''' [[SigE]] {{PubMed|15699190,2841290}}, [[SigK]] {{PubMed|2841290}}
+* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190,2841290}}, [[SigK]] {{PubMed|2841290}}
 * '''Regulation:'''
@@ Line 132: / Line 128: @@
 * '''Additional information:'''
-** [[SigK]] is activated by processing of membrane-bound pro-[[SigK]] by the [[SpoIVFB]] metalloprotease {{PubMed|19805276}}
+** [[SigK]] is activated by processing of membrane-bound pro-[[SigK]] by the [[SpoIVFB]] metalloprotease {{PubMed|23585539,19805276}}
 ** ''spoIVCB'' and ''[[spoIIIC]]'' form a composite gene in the mother cell during sporulation by excising the intervening DNA sequence.
@@ Line 163: / Line 159: @@
 ==Original Publications==
-<pubmed>14526016,17720779,1900494,10438769,2492118,1691789,2536191,2163341,10931284,1577688,9852018,1942049,7814326,8550479,11959848,9501233,10400595,2115401,7592342,1518043,8226681,9078383,2514119,10611287,14523132, 19805276 10075739 7966271 17890309 </pubmed>
+<pubmed>14526016,17720779,1900494,10438769,2492118,1691789,2536191,2163341,10931284,1577688,9852018,1942049,7814326,8550479,11959848,9501233,10400595,2115401,7592342,1518043,8226681,9078383,2514119,10611287,14523132, 19805276 10075739 7966271 17890309 23585539</pubmed>
 [[Category:Protein-coding genes]]