RuvA - Revision history

Jstuelk: /* Original publications */

2015-08-10T11:00:49Z

‎Original publications

Jstuelk at 16:47, 5 May 2014

2014-05-05T16:47:28Z

Jstuelk: /* The gene */

2014-05-05T10:27:13Z

‎The gene

Jstuelk at 10:21, 5 May 2014

2014-05-05T10:21:09Z

134.76.38.147 at 14:23, 2 April 2014

2014-04-02T14:23:09Z

Jstuelk at 17:56, 14 December 2013

2013-12-14T17:56:23Z

134.76.70.252 at 09:00, 12 November 2013

2013-11-12T09:00:41Z

Jstuelk at 16:29, 13 September 2013

2013-09-13T16:29:56Z

134.76.70.252 at 14:08, 16 May 2013

2013-05-16T14:08:24Z

134.76.70.252 at 10:52, 14 May 2013

2013-05-14T10:52:46Z

← Older revision		Revision as of 11:00, 10 August 2015
Line 1:		Line 1:
−	* '''Description:~~''' Holliday junction DNA helicase, part of the [[~~RuvA~~]]-[[RuvB]] branch migration translocase <br/><br/>~~	+	{{#bank: RuvA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''ruvA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| Holliday junction DNA helicase~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| [[DNA repair/ recombination]]~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27740 ruvA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RuvA RuvA]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 22 kDa, 5.384~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 603 bp, 201 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[ruvB]]'', ''[[bofC]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27740 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27740 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27740 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:ruvA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ruvA_2836165_2836770_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:ruvA_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27740]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[DNA repair/ recombination]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[LexA regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU27740
−
−	~~===Phenotypes of a mutant ===~~
−	* the inactivations of ''[[recU]]'' and ''[[ruvA]]-[[ruvB]]'' are synthetically lethal {{PubMed\|24770420}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27740&redirect=T BSU27740]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ruvAB.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11973]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−	** inhibits resolution of Holliday junctions by [[RecU]]-[[RuvB]] {{PubMed\|24770420}}
−
−	* '''Protein family:''' ruvA family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[RuvA]]-[[RuvB]]
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27740&redirect=T BSU27740]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/O05392 O05392]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27740]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−	* '''Operon:''' ''[[ruvA]]-[[ruvB]]'' {{PubMed\|16267290}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ruvA_2836165_2836770_-1 ruvA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−
−	* '''Regulation:'''
−	** induced upon DNA damage ([[LexA]]) {{PubMed\|16267290}}
−
−	* '''Regulatory mechanism:'''
−	** [[LexA]]: transcription repression {{PubMed\|16267290}}
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−	** 1A896 (no resistance), {{PubMed\|16020779}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A896&Search=1A896 BGSC]
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~== Reviews ==~~
−	~~<pubmed> 22933559 9442895</pubmed>~~
−	~~== Original publications ==~~
−	~~<pubmed>16267290, 24770420 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

← Older revision		Revision as of 16:47, 5 May 2014
Line 68:		Line 68:

	* '''Catalyzed reaction/ biological activity:'''		* '''Catalyzed reaction/ biological activity:'''
		+	** inhibits resolution of Holliday junctions by [[RecU]]-[[RuvB]] {{PubMed\|24770420}}

	* '''Protein family:''' ruvA family (according to Swiss-Prot)		* '''Protein family:''' ruvA family (according to Swiss-Prot)

@@ Line 52: / Line 52: @@
 ===Phenotypes of a mutant ===
 === Database entries ===
@@ Line 61: / Line 62: @@
 === Additional information===
 =The protein=

@@ Line 1: / Line 1: @@
-* '''Description:''' Holliday junction DNA helicase <br/><br/>
+* '''Description:''' Holliday junction DNA helicase, part of the [[RuvA]]-[[RuvB]] branch migration translocase <br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 12: / Line 12: @@
 |style="background:#ABCDEF;" align="center"| '''Product''' || Holliday junction DNA helicase
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || recombination
+|style="background:#ABCDEF;" align="center"|'''Function''' || [[DNA repair/ recombination]]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27740 ruvA]
@@ Line 61: / Line 61: @@
 === Additional information===
@@ Line 143: / Line 141: @@
 <pubmed> 22933559 9442895</pubmed>
 == Original publications ==
-<pubmed>16267290, </pubmed>
+<pubmed>16267290, 24770420 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 54: / Line 54: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ruvAB.html]
@@ Line 92: / Line 93: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 78: / Line 78: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 139: / Line 139: @@
 =References=
 == Reviews ==
-<pubmed> 22933559 </pubmed>
+<pubmed> 22933559 9442895</pubmed>
 == Original publications ==
 <pubmed>16267290, </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27740 ruvA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RuvA RuvA]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RuvA RuvA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.384

@@ Line 37: / Line 37: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 112: / Line 108: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ruvA_2836165_2836770_-1 ruvA] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 * '''Regulation:'''
@@ Line 142: / Line 138: @@
 =References=
+== Reviews ==
 <pubmed>16267290, </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ruvA_2836165_2836770_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ruvA_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ruvA_2836165_2836770_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ruvA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27740]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ruvB]]'', ''[[bofC]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27740 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27740 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27740 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27740 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27740 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27740 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:ruvA_context.gif]]