View source for Protein kinases and phosphatases

These enzymes phosphorylate or dephosphorylate other [[phosphoproteins|proteins]]. By definition, they use ATP (or GTP) as the phosphoryl group donor (as opposed to phosphotransferases of the [[PTS|phosphotranferase system]] and the [[phosphorelay]]).

==Protein kinases==
===Protein arginine kinases===
* [[McsB]]  

===Protein serine kinases===
* [[HprK]] (has also phosphorylase activity)
* [[PrkC]]
* [[PrkD]]
* [[RsbT]]
* [[RsbW]]
* [[SpoIIAB]]
* [[YabT]]

===Protein tyrosine kinases (see the [http://bykdb.ibcp.fr/BYKdb/BYKdbHelp Bacterial Protein Tyrosine Kinase Database])===
* [[PtkA]]
* [[EpsB]]: similar to [[PtkA]], but has probably no kinase activity

===Protein kinases of [[two-component systems]]===
* [[ComP]]
* [[DegS]]
* [[DesK]]
* [[LiaS]]
* [[YdfH]]
* [[YfiJ]]
* [[YhcY]]
* [[YvfT]]
* [[YxjM]]
* [[BceS]]
* [[CssS]]
* [[NatK]]
* [[PhoR]]
* [[ResE]]
* [[WalK]]
* [[YbdK]]
* [[YcbM]]
* [[YclK]]
* [[YkoH]]
* [[YrkO]]
* [[YvcQ]]
* [[YvrG]]
* [[YxdK]]
* [[CheA]]
* [[CitS]]
* [[DctS]]
* [[GlnK]]
* [[MalK]]
* [[LytS]]
* [[YesM]]
* [[YwpD]] 
* [[KinA]]
* [[KinB]]
* [[KinC]]
* [[KinD]]
* [[KinE]]

==Protein phosphatases==
===Protein arginine phosphatases===
* [[YwlE]] 

===Protein serine phosphatases===
* [[PrpC]]
* [[RsbP]]
* [[RsbU]]
* [[RsbX]]
* [[SpoIIE]]

===Protein tyrosine phosphatases===
* [[PtpZ]]
* [[YfkJ]]

===Protein aspartate phosphatases controlling the [[phosphorelay]] ===
* [[Spo0E]]: dephosphorylation of [[Spo0A]]
* [[YisI]]: dephosphorylation of [[Spo0A]]
* [[YnzD]]: dephosphorylation of [[Spo0A]]
* [[RapA]]: dephosphorylation of [[Spo0F]]
* [[RapB]]: dephosphorylation of [[Spo0F]]
* [[RapE]]: dephosphorylation of [[Spo0F]]
* [[RapH]]: dephosphorylation of [[Spo0F]]

=Related Lists=
* [[phosphoproteins]]
* [[protein modification]]
* [[two-component systems]]

=Reviews=
<pubmed> 26458398 16209347 21372323 23731382 25625314</pubmed>