SubtiWiki - User contributions [en]

Sporulation

2013-05-13T08:39:28Z

Jgib: /* Newly identified sporulation proteins (based on transcription profiling) */

{{CategoryTree
|Parents=
* 4. [[Lifestyles]]
** 4.2. [[Sporulation and Germination]]
|Neighbours=
* 4.2.1. [[Sporulation proteins]]
* 4.2.2. [[Phosphorelay]]
* 4.2.3. [[Sporulation/ other]]
* 4.2.4. [[Germination]]
|Related=
* {{SubtiWiki regulon|[[SigE regulon]]}}
* {{SubtiWiki regulon|[[SigF regulon]]}}
* {{SubtiWiki regulon|[[SigG regulon]]}}
* {{SubtiWiki regulon|[[SigK regulon]]}}
|}}

== Genes in this functional category ==

=== Spore coat proteins ===
==== Class I ====
* these proteins completly cover the membrane around the forespore
* early localizing spore coat proteins

* ''[[spoIVA]]''
* ''[[spoVM]]''
* ''[[spoVID]]''
* ''[[yaaH]]''
* ''[[yhaX]]''
* ''[[yuzC]]''

==== Class II ====
* these proteins localize simultaneously with the class I proteins but begin to encase the spore only after engulfment is complete
* early localizing spore coat proteins

* ''[[cotE]]''
* ''[[cotM]]''
* ''[[cotO]]''
* ''[[yncD]]''
* ''[[yheD]]''
* ''[[yknT]]''
* ''[[yhjR]]''

==== Class III ====
* these proteins localize simultaneously with the class I and class II proteins but start to encase the spore only after the appearance of phase dark spores (hr 4.5)
* early localizing spore coat proteins

* ''[[cotZ]]''
* ''[[cwlJ]]''
* ''[[tgl]]''
* ''[[yisY]]''
* ''[[ysxE]]''
* ''[[yutH]]''

==== Class IV ====
* late localizing spore coat proteins (only after completion of engulfment)
* intermediate between classes III and V

==== Class V ====
* late localizing spore coat proteins (only after completion of engulfment)
* localize exclusively to phase dark spores
* localize simultaneously to both poles of the spore

==== Class VI ====
* late localizing spore coat proteins (only after completion of engulfment)
* most delayed initial localization
* localize excluseively to phase bright spores

* ''[[cgeA]]''
* ''[[cmpA]]''
* ''[[cotA]]''
* ''[[cotB]]''
* ''[[cotC]]''
* ''[[cotD]]''

* ''[[cotF]]''
* ''[[cotG]]''
* ''[[cotH]]''
* ''[[cotI]]''
* ''[[cotJA]]''
* ''[[cotJB]]''
* ''[[cotJC]]''

* ''[[cotP]]''
* ''[[cotQ]]''
* ''[[cotS]]''
* ''[[cotSA]]''
* ''[[cotT]]''
* ''[[cotU]]''
* ''[[cotV]]''
* ''[[cotW]]''
* ''[[cotX]]''
* ''[[cotY]]''

* ''[[gerQ]]''
* ''[[gerR]]''
* ''[[gerT]]''
* ''[[lipC]]''
* ''[[oxdD]]''

* ''[[yeeK]]''
* ''[[ymaG]]''
* ''[[ysnD]]''
* ''[[ytxO]]''
* ''[[yxeE]]''

====Important publications on the spore coat====
'''Additional publications:''' {{PubMed|22262582}}
<pubmed> 22171814 20451384 22192522 23202530 </pubmed>

=== Spore coat protein/ based on similarity ===
* ''[[yraD]]''
* ''[[yraE]]''
* ''[[yraF]]''
* ''[[yraG]]''

=== Small acid-soluble spore proteins ===
* ''[[sspA]]''
* ''[[sspB]]''
* ''[[sspC]]''
* ''[[sspD]]''
* ''[[sspE]]''
* ''[[sspF]]''
* ''[[sspG]]''
* ''[[sspH]]''
* ''[[sspI]]''
* ''[[sspJ]]''
* ''[[sspK]]''
* ''[[sspL]]''
* ''[[sspM]]''
* ''[[sspN]]''
* ''[[sspO]]''
* ''[[sspP]]''

=== Sporulation proteins/ other ===
* ''[[adhB]]''
* ''[[asd]]''
* ''[[asnO]]''
* ''[[azoR2]]''
* ''[[bdbC]]''
* ''[[bdbD]]''
* ''[[bofA]]''
* ''[[bofC]]''
* ''[[ccpB]]''
* ''[[cdaS]]''
* ''[[cgeB]]''
* ''[[cgeC]]''
* ''[[cgeD]]''
* ''[[cgeE]]''
* ''[[chaA]]''
* ''[[clpC]]''
* ''[[cotR]]''
* ''[[coxA]]''
* ''[[csbX]]''
* ''[[ctaA]]''
* ''[[ctpB]]''
* ''[[cwlC]]''
* ''[[cwlH]]''
* ''[[dacB]]''
* ''[[dacF]]''
* ''[[dapA]]''
* ''[[dapG]]''
* ''[[divIB]]''
* ''[[divIC]]''
* ''[[exoA]]''
* ''[[exuR]]''
* ''[[exuT]]''
* ''[[fabL]]''
* ''[[fin]]''
* ''[[fisB]]''
* ''[[ftsY]]''
* ''[[gin]]''
* ''[[glcU]]''
* ''[[glgA]]''
* ''[[glgB]]''
* ''[[glgC]]''
* ''[[glgD]]''
* ''[[glgP]]''
* ''[[glnH]]''
* ''[[glnM]]''
* ''[[glnP]]''
* ''[[glnQ]]''
* ''[[ispG]]''
* ''[[kamA]]''
* ''[[katX]]''
* ''[[ksgA]]''
* ''[[ldt]]''
* ''[[lonB]]''
* ''[[lysA]]''
* ''[[lytH]]''
* ''[[mbl]]''
* ''[[mcsA]]''
* ''[[mcsB]]''
* ''[[mmgA]]''
* ''[[mmgB]]''
* ''[[mmgC]]''
* ''[[mmgD]]''
* ''[[mmgE]]''
* ''[[murB]]''
* ''[[murG]]''
* ''[[mutTA]]''
* ''[[nfo]]''
* ''[[pbpF]]''
* ''[[pbpG]]''
* ''[[pbpI]]''
* ''[[pdaB]]''
* ''[[phoB]]''
* ''[[phoP]]''
* ''[[phoR]]''
* ''[[prkA]]''
* ''[[remA]]''
* ''[[rsfA]]''
* ''[[safA]]''
* ''[[sbp]]''
* ''[[scoA]]''
* ''[[scoB]]''
* ''[[seaA]]''
* ''[[sigF]]''
* ''[[sigG]]''
* ''[[sodF]]''
* ''[[splA]]''
* ''[[splB]]''
* ''[[spmA]]''
* ''[[spmB]]''
* ''[[spoIIAA]]''
* ''[[spoIIAB]]''
* ''[[spoIID]]''
* ''[[spoIIIAA]]''
* ''[[spoIIIAB]]''
* ''[[spoIIIAC]]''
* ''[[spoIIIAD]]''
* ''[[spoIIIAE]]''
* ''[[spoIIIAF]]''
* ''[[spoIIIAG]]''
* ''[[spoIIIAH]]''
* ''[[spoIIIC]]''
* ''[[spoIIID]]''
* ''[[spoIIM]]''
* ''[[spoIIP]]''
* ''[[spoIIQ]]''
* ''[[spoIIR]]''
* ''[[spoIISA]]''
* ''[[spoIVA]]''
* ''[[spoIVB]]''
* ''[[spoIVCA]]''
* ''[[spoIVCB]]''
* ''[[spoIVFA]]''
* ''[[spoIVFB]]''
* ''[[spoVAA]]''
* ''[[spoVAB]]''
* ''[[spoVAC]]''
* ''[[spoVAF]]''
* ''[[spoVB]]''
* ''[[spoVD]]''
* ''[[spoVE]]''
* ''[[spoVFA]]''
* ''[[spoVFB]]''

* ''[[spoVIF]]''
* ''[[spoVK]]''

* ''[[spoVR]]''
* ''[[spoVT]]''
* ''[[spsA]]''
* ''[[spsB]]''
* ''[[spsC]]''
* ''[[spsD]]''
* ''[[spsE]]''
* ''[[spsF]]''
* ''[[spsG]]''
* ''[[spsI]]''
* ''[[spsJ]]''
* ''[[spsK]]''
* ''[[spsL]]''
* ''[[sqhC]]''
* ''[[sscA]]''
* ''[[stoA]]''
* ''[[tepA]]''
* ''[[tlp]]''
* ''[[tuaF]]''
* ''[[tuaG]]''
* ''[[tuaH]]''
* ''[[usd]]''
* ''[[uxaA]]''
* ''[[uxaB]]''
* ''[[uxuA]]''
* ''[[yabG]]''
* ''[[yabP]]''
* ''[[yabQ]]''
* ''[[yabR]]''
* ''[[yabT]]''
* ''[[ybaK]]''
* ''[[ybxH]]''
* ''[[ycgF]]''
* ''[[ycgG]]''
* ''[[yckC]]''
* ''[[yckD]]''
* ''[[ydcA]]''
* ''[[ydcC]]''
* ''[[ydfR]]''
* ''[[ydfS]]''
* ''[[ydgA]]''
* ''[[ydgB]]''
* ''[[ydhD]]''
* ''[[ydhF]]''
* ''[[ydjP]]''
* ''[[yeaA]]''
* ''[[yesJ]]''
* ''[[yesK]]''
* ''[[yfnD]]''
* ''[[yfnE]]''
* ''[[yfnF]]''
* ''[[yfnG]]''
* ''[[yfnH]]''
* ''[[yhaL]]''

* ''[[yhbH]]''
* ''[[yhcM]]''
* ''[[yhcN]]''
* ''[[yhcO]]''
* ''[[yhcQ]]''
* ''[[yhcV]]''
* ''[[yheC]]''

* ''[[yhfM]]''
* ''[[yhfW]]''

* ''[[yhxC]]''

* ''[[yisZ]]''
* ''[[yitA]]''
* ''[[yitB]]''
* ''[[yitC]]''
* ''[[yitD]]''
* ''[[yitF]]''
* ''[[yitG]]''
* ''[[yjaV]]''
* ''[[yjbA]]''
* ''[[yjcA]]''
* ''[[yjdH]]''
* ''[[yjfA]]''
* ''[[yjmC]]''
* ''[[yjmD]]''
* ''[[yjmF]]''

* ''[[ykoU]]''
* ''[[ykoV]]''
* ''[[ykvI]]''
* ''[[ykvP]]''
* ''[[ykvQ]]''
* ''[[ylaJ]]''
* ''[[ylaM]]''
* ''[[ylbB]]''
* ''[[ylbC]]''
* ''[[ylbD]]''
* ''[[ylbE]]''
* ''[[ylbJ]]''
* ''[[ylmC]]''
* ''[[ylxW]]''
* ''[[ylxX]]''
* ''[[ylyA]]''
* ''[[ylzJ]]''
* ''[[ymxH]]''
* ''[[yndA]]''
* ''[[yndL]]''
* ''[[yngE]]''
* ''[[yngF]]''
* ''[[yngG]]''
* ''[[yngH]]''
* ''[[yngHB]]''
* ''[[yngI]]''
* ''[[yngJ]]''
* ''[[yoaR]]''
* ''[[yoaW]]''
* ''[[yobW]]''
* ''[[yocL]]''
* ''[[yodH]]''
* ''[[yodI]]''
* ''[[yodP]]''
* ''[[yodQ]]''
* ''[[yodR]]''
* ''[[yodS]]''
* ''[[yodT]]''

* ''[[yokU]]''
* ''[[yozQ]]''

* ''[[ypfB]]''
* ''[[yphA]]''
* ''[[ypjB]]''
* ''[[ypqA]]''
* ''[[ypzA]]''
* ''[[yqcK]]''
* ''[[yqfC]]''
* ''[[yqfD]]''
* ''[[yqfQ]]''
* ''[[yqfU]]''
* ''[[yqfX]]''
* ''[[yqfZ]]''
* ''[[yqhG]]''
* ''[[yqhH]]''
* ''[[yqhP]]''
* ''[[yqhQ]]''
* ''[[yqiQ]]''
* ''[[yqxA]]''
* ''[[yqzG]]''
* ''[[yrkC]]''
* ''[[yrrD]]''
* ''[[yrrS]]''
* ''[[ytaF]]''
* ''[[ytcC]]''
* ''[[yteA]]''
* ''[[yteV]]''
* ''[[ytfI]]''
* ''[[ytfJ]]''
* ''[[ytlA]]''
* ''[[ytlC]]''
* ''[[ytlD]]''
* ''[[ytrH]]''
* ''[[ytrI]]''
* ''[[ytvI]]''
* ''[[ytxC]]''
* ''[[yuiC]]''

* ''[[yurS]]''
* ''[[yusN]]''
* ''[[yuzA]]''

* ''[[yvdQ]]''
* ''[[yveA]]''
* ''[[ywcA]]''
* ''[[ywcB]]''
* ''[[ywjD]]''
* ''[[ywjE]]''

* ''[[ywnJ]]''
* ''[[ywrJ]]''
* ''[[yxeD]]''
* ''[[yxjC]]''
* ''[[yxjF]]''
* ''[[yyaC]]''
* ''[[yyaD]]''
* ''[[yybI]]''
* ''[[yyxA]]''

=== Newly identified sporulation proteins (based on transcription profiling) ===
* ''[[araL]]''
* ''[[araM]]''
* ''[[citA]]''
* ''[[citH]]''
* ''[[lpiD]]''
* ''[[xpaC]]''
* ''[[yaaC]]''
* ''[[yabS]]''
* ''[[ybbC]]''
* ''[[ybeF]]''
* ''[[ybfJ]]''
* ''[[ycgI]]''
* ''[[ycgL]]''
* ''[[yerA]]''
* ''[[yetF]]''
* ''[[yfhM]]''
* ''[[yfhS]]''
* ''[[yflJ]]''
* ''[[yflN]]''
* ''[[yfmA]]''
* ''[[ygaK]]''
* ''[[yhaR]]''
* ''[[yhbB]]''
* ''[[yhcT]]''
* ''[[yhcW]]''
* ''[[yhdB]]''
* ''[[yhdC]]''
* ''[[yhdF]]''
* ''[[yheF]]''
* ''[[yhfA]]''
* ''[[yhfN]]''
* ''[[yhjQ]]''
* ''[[yisJ]]''
* ''[[yisN]]''
* ''[[yitE]]''
* ''[[yitQ]]''
* ''[[yjaZ]]''
* ''[[yjbE]]''
* ''[[yjnA]]''
* ''[[yjqC]]''
* ''[[yjzB]]''
* ''[[ykjA]]''
* ''[[ykoN]]''
* ''[[ykoP]]''
* ''[[ykoQ]]''
* ''[[ykoS]]''
* ''[[ykoT]]''
* ''[[ykoY]]''
* ''[[ykpC]]''
* ''[[ykuS]]''
* ''[[ykwB]]''
* ''[[ykzD]]''
* ''[[ykzE]]''
* ''[[ykzH]]''
* ''[[ylaK]]''
* ''[[ylxY]]''
* ''[[ymaF]]''
* ''[[ymfH]]''
* ''[[ymfI]]''
* ''[[ymfJ]]''
* ''[[yndM]]''
* ''[[ynfE]]''
* ''[[yngK]]''
* ''[[yngL]]''
* ''[[ynzE]]''
* ''[[yoaI]]''
* ''[[yoaM]]''
* ''[[yoaQ]]''
* ''[[yobN]]''
* ''[[yodL]]''
* ''[[yodN]]''
* ''[[yojB]]''
* ''[[yotE]]''
* ''[[yotG]]''
* ''[[yozD]]''
* ''[[yozE]]''
* ''[[yozF]]''
* ''[[yozN]]''
* ''[[ypeP]]''
* ''[[ypeQ]]''
* ''[[yppC]]''
* ''[[yppD]]''
* ''[[yppG]]''
* ''[[yptA]]''
* ''[[ypzC]]''
* ''[[yqeC]]''
* ''[[yqfT]]''
* ''[[yqgE]]''
* ''[[yqgO]]''
* ''[[yqhO]]''
* ''[[yqhR]]''
* ''[[yqhV]]''
* ''[[yqjB]]''
* ''[[yqjC]]''
* ''[[yrbE]]''
* ''[[yrbG]]''
* ''[[yrdN]]''
* ''[[yrrI]]''
* ''[[yrrT]]''
* ''[[yrzA]]''
* ''[[yrzE]]''
* ''[[yrzK]]''
* ''[[ysnE]]''
* ''[[ytcA]]''
* ''[[ytcB]]''
* ''[[ytdA]]''
* ''[[yteT]]''
* ''[[ytvB]]''
* ''[[ytwI]]''
* ''[[ytzC]]''
* ''[[ytzH]]''
* ''[[yubC]]''
* ''[[yueG]]''
* ''[[yufS]]''
* ''[[yugF]]''
* ''[[yumB]]''
* ''[[yunC]]''
* ''[[yurZ]]''
* ''[[yusW]]''
* ''[[yutC]]''
* ''[[yutG]]''
* ''[[yuzE]]''
* ''[[yuzF]]''
* ''[[yvaC]]''
* ''[[yvaG]]''
* ''[[yvaK]]''
* ''[[yvaM]]''
* ''[[yvdA]]''
* ''[[ywaF]]''
* ''[[ywbB]]''
* ''[[ywkF]]''
* ''[[ywmA]]''
* ''[[ywnG]]''
* ''[[ywoC]]''
* ''[[yxbA]]''
* ''[[yyaL]]''
* ''[[yybP]]''
* ''[[yycN]]''
* ''[[yycO]]''
* ''[[yycP]]''
* ''[[yycQ]]''
* ''[[yyzB]]''

==Important reviews==
'''Additional reviews:''' {{PubMed|22882546}}
<pubmed>22091839 20833318 16045607 15819616 15659154 15556029 15187183 15035041 2257467 </pubmed>

==Important original publications==
<pubmed>21667307 21665972 21905219 23284278 </pubmed>

=Back to [[categories]]=

YkoT

2013-05-08T13:53:01Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' similar to dolichol phosphate mannose synthase 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ykoT''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU13390 ykoT]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 38 kDa, 9.335
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1011 bp, 337 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ykoS]]'', ''[[ykoU]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB13196]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:ykoT_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ykoT_1403479_1404492_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:ykoT_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[membrane proteins]]}},
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU13390

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13263]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' glycosyltransferase 2 family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''
** [[YkoT]] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [[SubtInteract|interactions]] {{PubMed|21630458}}

* '''[[Localization]]:'''
** cell membrane (heterogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O34755 O34755]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU13390]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ykoT_1403479_1404492_1 ykoT] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=
<pubmed>21630458 16479537</pubmed>
[[Category:Protein-coding genes]]

YhdF

2013-05-08T13:51:35Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' similar to glucose 1-dehydrogenase 
{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yhdF''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU09450 yhdF]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 5.161
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 867 bp, 289 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[citA]]'', ''[[bcaP]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12784]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:yhdF_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yhdF_1022231_1023100_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yhdF_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}},
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigB regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU09450

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yhdF.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13012]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O07575 O07575]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU09450]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''ydhF'' (according to [http://dbtbs.hgc.jp/COG/prom/yhdF.html DBTBS])

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yhdF_1022231_1023100_1 yhdF] {{PubMed|22383849}}

* '''Sigma factor:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed]

* '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed]

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>11544224, </pubmed>

[[Category:Protein-coding genes]]

YhcW

2013-05-08T13:51:06Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' putative glycerol-3-phosphatase 
{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yhcW''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU09240 yhcW]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 4.631
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 660 bp, 220 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yhcV]]'', ''[[yhcX]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12752]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:yhcW_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yhcW_997724_998386_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yhcW_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU09240

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11601]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''
** glycerol-3-phosphate --> glycerol + inorganic phosphate {{PubMed|22353596}}

* '''Protein family:''' CbbY/cbbZ/gph/yieH family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P54607 P54607]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU09240]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''[[yhcW]]-[[yhcX]]''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yhcW_997724_998386_1 yhcW] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=
<pubmed> 22353596 </pubmed>
[[Category:Protein-coding genes]]

YhaR

2013-05-08T13:50:08Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' similar to enoyl CoA hydratase 
{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yhaR''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU09880 yhaR]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 6.355
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 765 bp, 255 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yhaS]]'', ''[[yhzD]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12828]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|-
|-
|colspan="2" | '''Genetic context''' [[Image:yhaR_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yhaR_1061491_1062258_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yhaR_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[membrane proteins]]}},
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[CcpA regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU09880

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12994]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''
** cell membrane (according to Swiss-Prot)

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O07533 O07533]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU09880]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yhaR_1061491_1062258_1 yhaR] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:''' repressed by glucose (17-fold) ([[CcpA]]) [http://www.ncbi.nlm.nih.gov/pubmed/12850135 PubMed]

* '''Regulatory mechanism:''' [[CcpA]]: transcription repression

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>12850135, </pubmed>

[[Category:Protein-coding genes]]

YgaK

2013-05-08T13:49:08Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' similar to reticuline oxidase 
{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ygaK''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU08800 ygaK]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 7.119
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1101 bp, 367 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[thiC]]'', ''[[senS]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12708]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|-
|-
|colspan="2" | '''Genetic context''' [[Image:ygaK_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ygaK_957705_959060_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:ygaK_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU08800

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12231]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' FAD-binding PCMH-type domain (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/Q796Y5 Q796Y5]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU08800]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''[[ygaK]]'' {{PubMed|22383849}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ygaK_957705_959060_-1 ygaK] {{PubMed|22383849}}

* '''[[Sigma factor]]:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=
<pubmed>22383849 </pubmed>
[[Category:Protein-coding genes]]

YfhM

2013-05-08T13:47:21Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' general stress protein, similar to epoxide hydrolase 
{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yfhM''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || survival of ethanol stress
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU08590 yfhM]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 32 kDa, 6.064
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 858 bp, 286 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yfhL]]'', ''[[csbB]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12687]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:yfhM_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfhM_929725_930585_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yfhM_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}},
{{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}},
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigB regulon]]}},
{{SubtiWiki regulon|[[SigW regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU08590

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yfhKLM.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12888]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' AB hydrolase superfamily (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O31581 O31581]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU08590]

* '''E.C. number:'''

=== Additional information===

:* subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed]
=Expression and regulation=

* '''Operon:''' ''[[yfhK]]-[[yfhL]]-[[yfhM]]'' {{PubMed|10913081}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yfhM_929725_930585_1 yfhM] {{PubMed|22383849}}

* '''Sigma factor:''' [[SigB]] {{PubMed|10913081,15805528}}, [[SigW]] {{PubMed|9987136}}

* '''Regulation:'''
** induced by stress ([[SigB]]) {{PubMed|10913081,15805528}}

* '''Regulatory mechanism:'''

* '''Additional information:''' subject to Clp-dependent proteolysis upon glucose starvation [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+17981983 PubMed]

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>9987136,10913081,,15805528, </pubmed>

[[Category:Protein-coding genes]]

YerA

2013-05-08T13:46:33Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' similar to adenine desaminase 
{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yerA''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU06560 yerA]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 66 kDa, 5.82
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1740 bp, 580 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yezF]]'', ''[[yerB]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12476]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:yerA_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yerA_713664_715406_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yerA_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[phosphoproteins]]}},
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU06560

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12829]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:''' Adenine + H2O = hypoxanthine + NH3 (according to Swiss-Prot)

* '''Protein family:''' adenine deaminase family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:''' phosphorylation on Ser-399 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed]

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O34909 O34909]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU06560]

* '''E.C. number:''' [http://www.expasy.org/enzyme/3.5.4.2 3.5.4.2]

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yerA_713664_715406_1 yerA] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>17218307, </pubmed>

[[Category:Protein-coding genes]]

XpaC

2013-05-08T13:43:02Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' hydrolysis of 5-bromo-4-chloroindolyl phosphate 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''xpaC''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU00250 xpaC]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 10.149
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 612 bp, 204 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gin]]'', ''[[yaaN]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB11801]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:xpaC_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=xpaC_35845_36459_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:xpaC_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}},
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SigW regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU00250

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/xpaC-yaaN.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10089]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P37467 P37467]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU00250]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''[[xpaC]]-[[yaaN]]''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=xpaC_35845_36459_1 xpaC] {{PubMed|22383849}}

* '''Sigma factor:''' [[SigW]] [http://www.ncbi.nlm.nih.gov/sites/entrez/9987136 PubMed]

* '''Regulation:''' expressed in stationary phase

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>9987136, </pubmed>

[[Category:Protein-coding genes]]

LplD

2013-05-08T13:39:13Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' hydrolytic enzyme 
{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''lplD''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU07130 lplD]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 49 kDa, 5.356
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1338 bp, 446 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[lplC]]'', ''[[yetF]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12532]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:lplD_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lplD_782958_784298_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:lplD_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU07130

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10858]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' glycosyl hydrolase 4 family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===

* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3FEF 3FEF]

* '''UniProt:''' [http://www.uniprot.org/uniprot/P39130 P39130]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU07130]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lplD_782958_784298_1 lplD] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

[[Category:Protein-coding genes]]

CitA

2013-05-08T13:37:35Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' minor citrate synthase 
{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''citA''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''citA1 ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || minor citrate synthase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU09440 citA]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 5.778
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1098 bp, 366 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[citR]], [[yhdF]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB12783]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|-
|-
|colspan="2" | '''Genetic context''' [[Image:citA_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=citA_1021057_1022157_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:citA_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[CitR regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU09440

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/citA.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10854]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:''' Acetyl-CoA + H2O + oxaloacetate = citrate + CoA (according to Swiss-Prot)

* '''Protein family:''' citrate synthase family (according to Swiss-Prot)

* '''Paralogous protein(s):''' [[MmgD]], [[CitZ]]

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===

* '''Structure:''' [http://www.proteopedia.org/wiki/index.php/2c6x 2C6X]

* '''UniProt:''' [http://www.uniprot.org/uniprot/P39119 P39119]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU09440]

* '''E.C. number:''' [http://www.expasy.org/enzyme/2.3.3.1 2.3.3.1]

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''citA'' {{PubMed|8045898}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=citA_1021057_1022157_1 citA] {{PubMed|22383849}}

* '''Sigma factor:''' [[SigA]] {{PubMed|8045898}}

* '''Regulation:'''

* '''Regulatory mechanism:''' [[CitR]]: transcription repression {{PubMed|8045899}}

* '''Additional information:'''

=Biological materials =

* '''Mutant:''' GP676 (erm), available in the [[Stülke]] lab

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>8045899,8045898, </pubmed>

[[Category:Protein-coding genes]]

AraM

2013-05-08T13:36:16Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' glycerol-1-phosphate dehydrogenase, L-arabinose operon 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''araM''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yseB ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || glycerol-1-phosphate dehydrogenase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of phosphoglycerolipids
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU28760 araM]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.628
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1182 bp, 394 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[araN]]'', ''[[araL]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14836]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:araM_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=araM_2943006_2944190_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:araM_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[membrane proteins]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[AraR regulon]]}},
{{SubtiWiki regulon|[[CcpA regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU28760

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/araABDLMNPQ-abfA.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11909]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:''' sn-glycerol-1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H (according to Swiss-Prot)

* '''Protein family:''' glycerol-1-phosphate dehydrogenase family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P94527 P94527]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU28760]

* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.261 1.1.1.261]

=== Additional information===

=Expression and regulation=
* '''Operon:''' ''[[araA]]-[[araB]]-[[araD]]-[[araL]]-[[araM]]-[[araN]]-[[araP]]-[[araQ]]-[[abfA]]'' {{PubMed|9084180}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=araM_2943006_2944190_-1 araM] {{PubMed|22383849}}

* '''Sigma factor:''' [[SigA]] {{PubMed|9084180}}

* '''Regulation:'''
** repressed by glucose ([[CcpA]]) {{PubMed|12949161}}
** induced by arabinose ([[AraR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]

* '''Regulatory mechanism:'''
** [[CcpA]]: transcription repression {{PubMed|12949161}}
** [[AraR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>18558723,9084180,,10417639,12949161 9084180, </pubmed>

[[Category:Protein-coding genes]]

AraL

2013-05-08T13:35:44Z

Jgib: /* Categories containing this gene/protein */

* '''Description:''' sugar phosphate phosphatase, L-arabinose operon 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''araL''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yseA ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || sugar phosphate phosphatase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || detoxification of accidental accumulation of phosphorylated metabolites
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU28770 araL]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 5.373
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 816 bp, 272 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[araM]]'', ''[[araD]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14837]+-newId sequences] (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' [[Image:araL_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=araL_2944187_2945005_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:araL_expression.png|500px]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[AraR regulon]]}},
{{SubtiWiki regulon|[[CcpA regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU28770

===Phenotypes of a mutant ===

=== Database entries ===

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/araABDLMNPQ-abfA.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11908]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' HAD superfamily

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)

=== Database entries ===

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P94526 P94526]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU28770]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=
* '''Operon:''' ''[[araA]]-[[araB]]-[[araD]]-[[araL]]-[[araM]]-[[araN]]-[[araP]]-[[araQ]]-[[abfA]]'' {{PubMed|9084180}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=araL_2944187_2945005_-1 araL] {{PubMed|22383849}}

* '''Sigma factor:''' [[SigA]] {{PubMed|9084180}}

* '''Regulation:'''
** repressed by glucose ([[CcpA]]) {{PubMed|12949161}}
** induced by arabinose ([[AraR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]

* '''Regulatory mechanism:'''
** [[CcpA]]: transcription repression {{PubMed|12949161}}
** [[AraR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=
'''Additional publications:''' {{PubMed|21575135}}
<pubmed>9084180 10417639 12949161</pubmed>
[[Category:Protein-coding genes]]