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2026-04-21T12:40:47Z
User contributions
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http://subtiwiki-test.uni-goettingen.de/wiki//index.php?title=FosB&diff=179379
FosB
2013-04-09T15:51:53Z
<p>Chamilton: /* References */</p>
<hr />
<div>* '''Description:''' bacillithiol-S-transferase; confers resistence against antimicrobial compounds from ''B. amyloliquefaciens'' <br/><br/><br />
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{| align="right" border="1" cellpadding="2" <br />
|-<br />
|style="background:#ABCDEF;" align="center"|'''Gene name'''<br />
|''fosB ''<br />
|-<br />
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yndN''<br />
|-<br />
|style="background:#ABCDEF;" align="center"| '''Essential''' || no <br />
|-<br />
|style="background:#ABCDEF;" align="center"| '''Product''' || fosfomycin resistance protein <br />
|-<br />
|style="background:#ABCDEF;" align="center"|'''Function''' || confers resistence against antimicrobial compounds <br/>from ''B. amyloliquefaciens''<br />
|-<br />
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU17840 fosB]<br />
|-<br />
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 6.137 <br />
|-<br />
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 432 bp, 144 aa <br />
|-<br />
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yndM]]'', ''[[lexA]]''<br />
|-<br />
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13668&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''<br />
|-<br />
|colspan="2" | '''Genetic context''' <br/> [[Image:yndN_context.gif]]<br />
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div><br />
|-<br />
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fosB_1916663_1917097_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:fosB_expression.png|500px]]<br />
|-<br />
|}<br />
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__TOC__<br />
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= [[Categories]] containing this gene/protein =<br />
{{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}},<br />
{{SubtiWiki category|[[resistance against toxins/ antibiotics]]}}<br />
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= This gene is a member of the following [[regulons]] =<br />
{{SubtiWiki regulon|[[SigW regulon]]}}<br />
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=The gene=<br />
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=== Basic information ===<br />
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* '''Locus tag:''' BSU17840<br />
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===Phenotypes of a mutant ===<br />
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=== Database entries ===<br />
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* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yndN.html]<br />
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* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13450]<br />
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=== Additional information===<br />
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=The protein=<br />
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=== Basic information/ Evolution ===<br />
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* '''Catalyzed reaction/ biological activity:''' <br />
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* '''Protein family:''' FosB subfamily (according to Swiss-Prot)<br />
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* '''Paralogous protein(s):'''<br />
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=== Extended information on the protein ===<br />
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* '''Kinetic information:''' <br />
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* '''Domains:''' <br />
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* '''Modification:'''<br />
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* '''Cofactor(s):'''<br />
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* '''Effectors of protein activity:'''<br />
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* '''[[SubtInteract|Interactions]]:''' <br />
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* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)<br />
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=== Database entries ===<br />
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* '''Structure:''' <br />
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* '''UniProt:''' [http://www.uniprot.org/uniprot/O31817 O31817]<br />
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU17840]<br />
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* '''E.C. number:'''<br />
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=== Additional information===<br />
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=Expression and regulation=<br />
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* '''Operon:''' ''fosB'' {{PubMed|11244082}}<br />
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fosB_1916663_1917097_1 fosB] {{PubMed|22383849}}<br />
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* '''Sigma factor:''' [[SigW]] {{PubMed|11244082}}<br />
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* '''Regulation:''' <br />
** expressed under stress conditions ([[SigW]]) {{PubMed|11244082}}<br />
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* '''Regulatory mechanism:''' <br />
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* '''Additional information:'''<br />
** A [[ncRNA]] is predicted between ''[[fosB]]'' and ''[[lexA]]'' {{PubMed|20525796}}<br />
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=Biological materials =<br />
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* '''Mutant:'''<br />
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* '''Expression vector:'''<br />
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* '''lacZ fusion:'''<br />
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* '''GFP fusion:'''<br />
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* '''two-hybrid system:''' <br />
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* '''Antibody:'''<br />
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=Labs working on this gene/protein=<br />
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=Your additional remarks=<br />
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=References=<br />
'''Additional publications:''' {{PubMed|20712413}}<br />
<pubmed>11244082,16629676, 20525796 23030527, 23256780 </pubmed><br />
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[[Category:Protein-coding genes]]<br />
23256780</div>
Chamilton