Explore the novel features of the upcoming release of
SubtiWiki in its beta version (a.k.a.
CoreWiki).
It features genomic conservation, interaction of proteins with metabolites, dedicated metabolite pages, and much more!
Check the pages for
MntR and
manganese!
bceR
168
two-component response regulator ([wiki|OmpR family]), regulation of [gene|8E0DE8FE7E9C12495C4DCADA74D838FED088867D|bceA]-[gene|search|bceB ]in response to external (bacitracin, plectasin, mersacidin and actagardine) and internal ([protein|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|sdpC], [protein|DDB0022F50999AC52809D651C9CC5A5FDC71302C|skfA]) antimicrobial peptides
Molecular weight
26.72 kDa
function
resistance against toxic peptides
product
two-component response regulator ([wiki|OmpR family])
Genomic Context
This gene is a member of the following
regulons
Gene
Coordinates
3,113,187 → 3,113,882
The protein
Protein family
[wiki|Domains]
[wiki|Response regulatory domain] (aa 3-116) (according to UniProt)
Structure
[PDB|1KGS] (DrrD from ''Thermotoga maritima '', 32% identity) [Pubmed|11839301]
[AF|O34951]
Modification
phosphorylated by [protein|08F24CA21DC54031F6158AC0C772F3B520E5A849|bceS] on an Asp residue
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|C239C155F5452C86BF6C78190BABBBB07A63DF87|bceR]-[gene|08F24CA21DC54031F6158AC0C772F3B520E5A849|bceS]
description
[Pubmed|12399481]
[gene|C239C155F5452C86BF6C78190BABBBB07A63DF87|bceR]→[gene|08F24CA21DC54031F6158AC0C772F3B520E5A849|bceS]
2024-10-05 13:09:38
ghost
56
0d9c5f5aba9cd37b65e502c54a394ddb9aea0053
3ED24B86B015CF9A9605EB84290EFCB74C536FCF
Biological materials
Mutant
GP3218 Δ([gene|C239C155F5452C86BF6C78190BABBBB07A63DF87|bceR]-[gene|08F24CA21DC54031F6158AC0C772F3B520E5A849|bceS]-[gene|8E0DE8FE7E9C12495C4DCADA74D838FED088867D|bceA]-[gene|E3613A6C8B5F0EC76510ACE3E478967E73E2B241|bceB])::''cat'', available in [wiki|Jörg Stülke]'s lab
MGNA-A133 (ytsA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/133 NBRP B. subtilis, Japan]
BKE30400 (Δ[gene|C239C155F5452C86BF6C78190BABBBB07A63DF87|bceR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE30400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATCGACTCACCGCACTTT, downstream forward: _UP4_ATCGCGAAGGAAGAGGACAA
BKK30400 (Δ[gene|C239C155F5452C86BF6C78190BABBBB07A63DF87|bceR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK30400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATCGACTCACCGCACTTT, downstream forward: _UP4_ATCGCGAAGGAAGAGGACAA
References
Reviews
27344142,28152228,29404338,33450852,38460782 Original Publications
10094672,18394148,12890034,14651641,21283517,20606066,17905982,25118291,22964256,21078927,26199330,26364265,11839301,27997719
