Nudix hydrolase
Nudix hydrolases are found in all classes of organism and hydrolyse a wide range of organic pyrophosphates, including nucleoside di- and triphosphates, dinucleoside and diphosphoinositol polyphosphates, nucleotide sugars and RNA caps, with varying degrees of substrate specificity.
Nudix hydrolases in Bacillus subtilis
Key reviews
A G McLennan
The Nudix hydrolase superfamily.
Cell Mol Life Sci: 2006, 63(2);123-43
[PubMed:16378245]
[WorldCat.org]
[DOI]
(P p)
A S Mildvan, Z Xia, H F Azurmendi, V Saraswat, P M Legler, M A Massiah, S B Gabelli, M A Bianchet, L-W Kang, L M Amzel
Structures and mechanisms of Nudix hydrolases.
Arch Biochem Biophys: 2005, 433(1);129-43
[PubMed:15581572]
[WorldCat.org]
[DOI]
(P p)
M J Bessman, D N Frick, S F O'Handley
The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes.
J Biol Chem: 1996, 271(41);25059-62
[PubMed:8810257]
[WorldCat.org]
[DOI]
(P p)
