Acquisition of iron

Parent categories	1. Cellular processes 1.3. Homeostasis
Neighbouring categories	1.3.1. Metal ion homeostasis (K, Na, Ca, Mg) 1.3.2. Trace metal homeostasis (Cu, Zn, Ni, Mn, Mo) 1.3.3. Acquisition of iron 1.3.4. pH homeostasis
Related categories	Iron metabolism Fur regulon
Overview on the categories (Excel file) All genes and their categories (Excel file)

• Note: the main systems for iron uptake in B. subtilis 168 are YfmF-YfmD-YfmE-YfmC-YhfQ and EfeO-EfeU with EfeB PubMed

ABC transporters for theuptake of iron/ siderophores

• YusV-FeuB-FeuC-FeuA: uptake of the siderophores enterobactin and bacillibactin
• FhuC-FhuB-FhuG-FhuD-YxeB: uptake of ferrichrome und ferrioxamine
• YclN-YclO-YclP-YclQ: uptake of petrobactin (a siderophore produced by B. anthracis and B. cereus)
• YusV-YfiZ-YfhA-YfiY: uptake of the siderophores schizokinen and arthrobactin
• YfmF-YfmD-YfmE-YfmC-YhfQ: uptake of iron/citrate

Elemental iron transport system

• EfeO-EfeU, EfeB

Other genes in this functional category

• besA
• btr
• cypX
• dhbA
• dhbB
• dhbC
• dhbE
• dhbF
• dps
• fbpA
• fbpB
• fbpC
• fur
• hmoA
• hmoB
• mrgA
• ybbA
• yfhA
• yfiY
• yfiZ
• ymfD
• ytpQ
• yvmB
• yvmC
• yxeB

Additional candidates (based on similarity)

• ytoA
• yvrA
• yvrB
• yvrC

Important original publications

Emily M Roy, Kevin L Griffith
Characterization of a Novel Iron Acquisition Activity That Coordinates the Iron Response with Population Density under Iron-Replete Conditions in Bacillus subtilis.
J Bacteriol: 2017, 199(1);
[PubMed:27795321] [WorldCat.org] [DOI] (I e)