Stusti 2018

Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

What makes RNA such a special molecule – specific chemical and structural features of RNA: Niklas Kehl

David A Hiller, Scott A Strobel
The chemical versatility of RNA.
Philos Trans R Soc Lond B Biol Sci: 2011, 366(1580);2929-35
[PubMed:21930584] [WorldCat.org] [DOI] (I p)

RNA synthesis – DNA and RNA dependent RNA polymerases and primase during transcription, replication and repair: Andrea Lehner

Savio T de Farias, Ariosvaldo P Dos Santos Junior, Thais G Rêgo, Marco V José
Origin and Evolution of RNA-Dependent RNA Polymerase.
Front Genet: 2017, 8;125
[PubMed:28979293] [WorldCat.org] [DOI] (P e)

Thomas A Guilliam, Benjamin A Keen, Nigel C Brissett, Aidan J Doherty
Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes.
Nucleic Acids Res: 2015, 43(14);6651-64
[PubMed:26109351] [WorldCat.org] [DOI] (I p)

Maria L Kireeva, Mikhail Kashlev, Zachary F Burton
RNA polymerase structure, function, regulation, dynamics, fidelity, and roles in gene expression.
Chem Rev: 2013, 113(11);8325-30
[PubMed:24219496] [WorldCat.org] [DOI] (I p)

S Buratowski
The basics of basal transcription by RNA polymerase II.
Cell: 1994, 77(1);1-3
[PubMed:8156586] [WorldCat.org] [DOI] (P p)

The Splicosome - the mechanism of mRNA splicing – alternative gene expression, genome size definition and phenotype plasticity: Christian Schneider

Panagiotis Papasaikas, Juan Valcárcel
The Spliceosome: The Ultimate RNA Chaperone and Sculptor.
Trends Biochem Sci: 2016, 41(1);33-45
[PubMed:26682498] [WorldCat.org] [DOI] (I p)

Yan Wang, Jing Liu, B O Huang, Yan-Mei Xu, Jing Li, Lin-Feng Huang, Jin Lin, Jing Zhang, Qing-Hua Min, Wei-Ming Yang, Xiao-Zhong Wang
Mechanism of alternative splicing and its regulation.
Biomed Rep: 2015, 3(2);152-158
[PubMed:25798239] [WorldCat.org] [DOI] (P p)

A Gregory Matera, Zefeng Wang
A day in the life of the spliceosome.
Nat Rev Mol Cell Biol: 2014, 15(2);108-21
[PubMed:24452469] [WorldCat.org] [DOI] (I p)

Riboregulation and virulence, targeting by antibiotics: Theresia Eisele

Juan J Quereda, Pascale Cossart
Regulating Bacterial Virulence with RNA.
Annu Rev Microbiol: 2017, 71;263-280
[PubMed:28886688] [WorldCat.org] [DOI] (I p)

Petra Dersch, Muna A Khan, Sabrina Mühlen, Boris Görke
Roles of Regulatory RNAs for Antibiotic Resistance in Bacteria and Their Potential Value as Novel Drug Targets.
Front Microbiol: 2017, 8;803
[PubMed:28529506] [WorldCat.org] [DOI] (P e)

Hao Wang, Paul A Mann, Li Xiao, Charles Gill, Andrew M Galgoci, John A Howe, Artjohn Villafania, Christopher M Barbieri, Juliana C Malinverni, Xinwei Sher, Todd Mayhood, Megan D McCurry, Nicholas Murgolo, Amy Flattery, Matthias Mack, Terry Roemer
Dual-Targeting Small-Molecule Inhibitors of the Staphylococcus aureus FMN Riboswitch Disrupt Riboflavin Homeostasis in an Infectious Setting.
Cell Chem Biol: 2017, 24(5);576-588.e6
[PubMed:28434876] [WorldCat.org] [DOI] (I p)

Andreas Matern, Danielle Pedrolli, Stephanie Großhennig, Jörgen Johansson, Matthias Mack
Uptake and Metabolism of Antibiotics Roseoflavin and 8-Demethyl-8-Aminoriboflavin in Riboflavin-Auxotrophic Listeria monocytogenes.
J Bacteriol: 2016, 198(23);3233-3243
[PubMed:27672192] [WorldCat.org] [DOI] (I e)

Aaron M Nuss, Ann Kathrin Heroven, Petra Dersch
RNA Regulators: Formidable Modulators of Yersinia Virulence.
Trends Microbiol: 2017, 25(1);19-34
[PubMed:27651123] [WorldCat.org] [DOI] (I p)

Daniel Dar, Maya Shamir, J R Mellin, Mikael Koutero, Noam Stern-Ginossar, Pascale Cossart, Rotem Sorek
Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria.
Science: 2016, 352(6282);aad9822
[PubMed:27120414] [WorldCat.org] [DOI] (I p)

John A Howe, Hao Wang, Thierry O Fischmann, Carl J Balibar, Li Xiao, Andrew M Galgoci, Juliana C Malinverni, Todd Mayhood, Artjohn Villafania, Ali Nahvi, Nicholas Murgolo, Christopher M Barbieri, Paul A Mann, Donna Carr, Ellen Xia, Paul Zuck, Dan Riley, Ronald E Painter, Scott S Walker, Brad Sherborne, Reynalda de Jesus, Weidong Pan, Michael A Plotkin, Jin Wu, Diane Rindgen, John Cummings, Charles G Garlisi, Rumin Zhang, Payal R Sheth, Charles J Gill, Haifeng Tang, Terry Roemer
Selective small-molecule inhibition of an RNA structural element.
Nature: 2015, 526(7575);672-7
[PubMed:26416753] [WorldCat.org] [DOI] (I p)

RNA degradation/processing: Lena Kricsfalussy-Hrabar

John C Zinder, Christopher D Lima
Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors.
Genes Dev: 2017, 31(2);88-100
[PubMed:28202538] [WorldCat.org] [DOI] (I p)

Soraya Aït-Bara, Agamemnon J Carpousis
RNA degradosomes in bacteria and chloroplasts: classification, distribution and evolution of RNase E homologs.
Mol Microbiol: 2015, 97(6);1021-135
[PubMed:26096689] [WorldCat.org] [DOI] (I p)

Jonathan Houseley, David Tollervey
The many pathways of RNA degradation.
Cell: 2009, 136(4);763-76
[PubMed:19239894] [WorldCat.org] [DOI] (I p)

Regulation by non-coding RNA: Maxin Drömer

Yvonne Göpel, Muna A Khan, Boris Görke
Ménage à trois: post-transcriptional control of the key enzyme for cell envelope synthesis by a base-pairing small RNA, an RNase adaptor protein, and a small RNA mimic.
RNA Biol: 2014, 11(5);433-42
[PubMed:24667238] [WorldCat.org] [DOI] (I p)

Boris Görke, Jörg Vogel
Noncoding RNA control of the making and breaking of sugars.
Genes Dev: 2008, 22(21);2914-25
[PubMed:18981470] [WorldCat.org] [DOI] (P p)

CRISPR/Cas: Science – the bacterial “immune” system: Maximilian Schreier

Yoshizumi Ishino, Mart Krupovic, Patrick Forterre
History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology.
J Bacteriol: 2018, 200(7);
[PubMed:29358495] [WorldCat.org] [DOI] (I e)

Lina M Leon, Senén D Mendoza, Joseph Bondy-Denomy
How bacteria control the CRISPR-Cas arsenal.
Curr Opin Microbiol: 2018, 42;87-95
[PubMed:29169146] [WorldCat.org] [DOI] (I p)

Fuguo Jiang, Jennifer A Doudna
CRISPR-Cas9 Structures and Mechanisms.
Annu Rev Biophys: 2017, 46;505-529
[PubMed:28375731] [WorldCat.org] [DOI] (I p)

Synthesis, maturation and function of tRNAs – The wobble hypothesis and specific codon usage as a molecular barrier for horizontal gene transfer: Artur Fornol

Tessa E F Quax, Nico J Claassens, Dieter Söll, John van der Oost
Codon Bias as a Means to Fine-Tune Gene Expression.
Mol Cell: 2015, 59(2);149-61
[PubMed:26186290] [WorldCat.org] [DOI] (I p)

Sibah Alkatib, Lars B Scharff, Marcelo Rogalski, Tobias T Fleischmann, Annemarie Matthes, Stefanie Seeger, Mark A Schöttler, Stephanie Ruf, Ralph Bock
The contributions of wobbling and superwobbling to the reading of the genetic code.
PLoS Genet: 2012, 8(11);e1003076
[PubMed:23166520] [WorldCat.org] [DOI] (I p)

Tamir Tuller
Codon bias, tRNA pools and horizontal gene transfer.
Mob Genet Elements: 2011, 1(1);75-77
[PubMed:22016848] [WorldCat.org] [DOI] (P p)

Richard Giegé, Frank Jühling, Joern Pütz, Peter Stadler, Claude Sauter, Catherine Florentz
Structure of transfer RNAs: similarity and variability.
Wiley Interdiscip Rev RNA: 2012, 3(1);37-61
[PubMed:21957054] [WorldCat.org] [DOI] (I p)

Ingo Wohlgemuth, Corinna Pohl, Joerg Mittelstaet, Andrey L Konevega, Marina V Rodnina
Evolutionary optimization of speed and accuracy of decoding on the ribosome.
Philos Trans R Soc Lond B Biol Sci: 2011, 366(1580);2979-86
[PubMed:21930591] [WorldCat.org] [DOI] (I p)

RNA dependent RNA Polymerases – the RNA replicase

Sangita Venkataraman, Burra V L S Prasad, Ramasamy Selvarajan
RNA Dependent RNA Polymerases: Insights from Structure, Function and Evolution.
Viruses: 2018, 10(2);
[PubMed:29439438] [WorldCat.org] [DOI] (I e)

Kenneth K S Ng, Jamie J Arnold, Craig E Cameron
Structure-function relationships among RNA-dependent RNA polymerases.
Curr Top Microbiol Immunol: 2008, 320;137-56
[PubMed:18268843] [WorldCat.org] [DOI] (P p)

E K O'Reilly, C C Kao
Analysis of RNA-dependent RNA polymerase structure and function as guided by known polymerase structures and computer predictions of secondary structure.
Virology: 1998, 252(2);287-303
[PubMed:9878607] [WorldCat.org] [DOI] (P p)

The mysterious function and role of 6S-RNA and pRNA in bacteria

Benedikt Steuten, Philipp G Hoch, Katrin Damm, Sabine Schneider, Karen Köhler, Rolf Wagner, Roland K Hartmann
Regulation of transcription by 6S RNAs: insights from the Escherichia coli and Bacillus subtilis model systems.
RNA Biol: 2014, 11(5);508-21
[PubMed:24786589] [WorldCat.org] [DOI] (I p)

Amy T Cavanagh, Karen M Wassarman
6S RNA, a global regulator of transcription in Escherichia coli, Bacillus subtilis, and beyond.
Annu Rev Microbiol: 2014, 68;45-60
[PubMed:24742053] [WorldCat.org] [DOI] (I p)

Amy T Cavanagh, Karen M Wassarman
6S-1 RNA function leads to a delay in sporulation in Bacillus subtilis.
J Bacteriol: 2013, 195(9);2079-86
[PubMed:23457253] [WorldCat.org] [DOI] (I p)

Karen M Wassarman
6S RNA: a small RNA regulator of transcription.
Curr Opin Microbiol: 2007, 10(2);164-8
[PubMed:17383220] [WorldCat.org] [DOI] (P p)

RNA thermometers

Johanna Roßmanith, Franz Narberhaus
Exploring the modular nature of riboswitches and RNA thermometers.
Nucleic Acids Res: 2016, 44(11);5410-23
[PubMed:27060146] [WorldCat.org] [DOI] (I p)

Satya Narayan, Mamta H Kombrabail, Sudipta Das, Himanshu Singh, Kandala V R Chary, Basuthkar J Rao, Guruswamy Krishnamoorthy
Site-specific fluorescence dynamics in an RNA 'thermometer' reveals the role of ribosome binding in its temperature-sensitive switch function.
Nucleic Acids Res: 2015, 43(1);493-503
[PubMed:25477380] [WorldCat.org] [DOI] (I p)